The FLI1 (1G5) Mouse mAb Antibody from MyBioSource.com is a Mouse Monoclonal antibody to FLI1. This antibody recognizes Human antigen. The FLI1 (1G5) Mouse mAb Antibody has been validated for the following applications: Immunohistochemistry, Immunohistochemistry - fixed, and Western Blot.
Description
Sequence-specific transcriptional activator (PubMed:24100448, PubMed:26316623, PubMed:28255014). Recognizes the DNA sequence 5'-C[CA]GGAAGT-3'.
This gene encodes a transcription factor containing an ETS DNA-binding domain. The gene can undergo a t(11;22)(q24;q12) translocation with the Ewing sarcoma gene on chromosome 22, which results in a fusion gene that is present in the majority of Ewing sarcoma cases. An acute lymphoblastic leukemia-associated t(4;11)(q21;q23) translocation involving this gene has also been identified. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]